PhTxGNN Drug Repurposing Reports

Philippine drug repurposing predictions using TxGNN knowledge graph.

Disclaimer: These predictions are for research purposes only. They do not constitute medical advice and require clinical validation before any clinical application.

Overview

PhTxGNN analyzes drugs from the Philippine National Formulary (PNF) using the TxGNN knowledge graph to identify potential new therapeutic uses for existing medications.

Key Statistics

Metric Value
PNF Drugs Analyzed 529
DrugBank Mapping Rate 85.4%
Drug-Indication Pairs 3,322
Unique Drugs with Indications 338
Unique Diseases 880

Data Sources

  • Philippine National Formulary (PNF): Essential Medicines List, 8th Edition (2022)
  • TxGNN Knowledge Graph: Drug-disease relationship predictions
  • DrugBank: Drug identifier mapping
  • FHIR API - Access predictions via FHIR R4 API
  • SMART App - Launch SMART on FHIR application

How It Works

  1. Drug Extraction: Extract drug names from PNF-EML 2022
  2. DrugBank Mapping: Map drug names to standard DrugBank identifiers
  3. TxGNN Prediction: Use knowledge graph to find potential indications
  4. FHIR Export: Generate FHIR R4 resources for interoperability

Contact

For questions or feedback, please open an issue on GitHub.


Last updated: 2026-07-26


About the Developer

This platform is developed and operated by 藥提醒科技有限公司 (yao.care, company registration number 83620786, 12F, No. 220, Sec. 2, Taiwan Blvd., West Dist., Taichung City, Taiwan).

PhTxGNN is the the Philippines site of the company’s “TxGNN Drug Repurposing” product line. The same system is deployed across 30 countries and regions, each named {CC}TxGNN (JpTxGNN, UsTxGNN, DETxGNN, and so on) at {cc}txgnn.yao.care. Product overview: https://www.yao.care/medical/txgnn/.

The TxGNN model itself was developed by the Zitnik Lab at Harvard Medical School and published in Nature Medicine. This platform is the production system 藥提醒科技有限公司 built on top of that model, covering national drug-registration data integration, dual knowledge-graph and deep-learning prediction, PubMed / ClinicalTrials evidence grading, and SMART on FHIR electronic health record integration.


Copyright © 2026 藥提醒科技有限公司 (yao.care). For research purposes only.

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