PhTxGNN Drug Repurposing Reports

Philippine drug repurposing predictions using TxGNN knowledge graph.

Disclaimer: These predictions are for research purposes only. They do not constitute medical advice and require clinical validation before any clinical application.

Overview

PhTxGNN analyzes drugs from the Philippine National Formulary (PNF) using the TxGNN knowledge graph to identify potential new therapeutic uses for existing medications.

Key Statistics

Metric	Value
PNF Drugs Analyzed	529
DrugBank Mapping Rate	85.4%
Drug-Indication Pairs	3,322
Unique Drugs with Indications	338
Unique Diseases	880

Data Sources

• Philippine National Formulary (PNF): Essential Medicines List, 8th Edition (2022)
• TxGNN Knowledge Graph: Drug-disease relationship predictions
• DrugBank: Drug identifier mapping

Quick Links

• FHIR API - Access predictions via FHIR R4 API
• SMART App - Launch SMART on FHIR application

How It Works

1. Drug Extraction: Extract drug names from PNF-EML 2022
2. DrugBank Mapping: Map drug names to standard DrugBank identifiers
3. TxGNN Prediction: Use knowledge graph to find potential indications
4. FHIR Export: Generate FHIR R4 resources for interoperability

Contact

For questions or feedback, please open an issue on GitHub.

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Last updated: 2026-03-08